Symptoms of this disease
The most significant symptoms are pain and swelling of the affected bone, resulting in restricted movement. In addition, a bone fracture may occur due to a lack of bone strength. Pain and possible nerve damage can occur during ingrowth in nerve tissue. In 15-35% of patients, metastases are found on diagnosis, mainly in the lungs, other bones and bone marrow.
How do we make the diagnosis?
A definitive diagnosis can only be made by obtaining tumor tissue using a biopsy. In addition, we take a bone photo and MRI scan of the location of the tumor. A CT scan of the lungs shows whether there are metastases here, a bone scan and a bone marrow puncture are required to assess whether there are metastases in the bones or bone marrow.
Treatment of Ewing sarcoma
The treatment of an Ewing sarcoma consists of a combination of chemotherapy, followed by surgery or radiation (radiotherapy). After the local treatment, there is often further chemotherapeutic after-treatment. For some children this is followed by therapy with a high dose of chemotherapy and a stem cell transplantation with the child's own stem cells. Sometimes the affected limb (arm or leg) needs to be amputated (see also osteosarcoma). If surgery is not required, radiation is a very important part of the treatment, in addition to chemotherapy.