Knowledge and Experience
Specialism/Sub specialism: Acute Lymphatic Leukemia (ALL)
Work Experience:
1987-1991 doctoral research, VU University Amsterdam
1991-1995: Pediatrician Training Program, VU University Medical Center (VUmc)
1995-1998: Pediatric Oncology Fellow, VUmc, Academic Medical Center (AMC) and Leiden University Medical Centre (LUMC)
1999-2014: Head of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital
2007-2014: co-initiator of the Princess Máxima Center
2013-present: member of the Board of Directors of the Princess Máxima Center
Scientific Research
1991: drug resistance in childhood leukemia, VU University of Amsterdam
2001-2017: Professor of Pediatric Cancer, Erasmus University
2017-present: Professor of Pediatric Oncology at Utrecht University
Publications
Pieters R., Huismans D.R., Loonen A.H., Hählen K., van der Does-van den Berg A., van Wering E.R., Veerman A.J.P. Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukemia. Lancet 1991; 338: 399-403.
Pieters R., Schrappe M., de Lorenzo P., Hann I., de Rossi G., Felice M., Hovi L., Leblance T., Szczepanski T., Ferster A., Janka G., Rubnitz J., Silverman L., Stary J., Campbell M., Li C.H., Mann G., Suppiah R., Biondi A., Vora A., Valsecchi M.G. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicenter randomized trial. Lancet 2007; 370:240-250.
Boer den ML, van Slegtenhorst M., De Menezes R.X., Cheok M.H., Buijs-Gladdines J.G.C.A.M., Peters S.T.C.J.M., van Zutven L.J.C.M., Beverloo H.B., van der Spek P.J., Escherich G., Horstmann M.A., Janka/Schaub G.E., Kamps W.A., Evans W.E., Pieters R. A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. The Lancet Oncology 2009;10:125-134.
Holleman A/Cheok M.H.*, den Boer M.L., Yang W., Veerman A.J., Kazemier K.M., Pei D., Cheng C., Pui C.H., Relling M.V., Janka-Schaub G.E., Pieters R./Evans W.E.* Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. The New England Journal of Medicine 2004;351:533-42. (*shared first and last authorship)
Pieters R., de Groot-Kruseman H.A., van der Velden V.H.J., Fiocco M., van den Berg H., de Bont E.S.J.M., Egeler R.M., Hoogerbrugge P.M., Kaspers G.J.L., van der Schoot C.E., de Haas V, van Dongen J.J.M. Successful therapy reduction and intensification for childhood acute lymphoblastic leukemia based on minimal residual disease monitoring: study ALL10 from the DCOG. Journal of Clinical Oncology 2016: 34:2591-2601.
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