Our website uses cookies. We use cookies to remember settings and to help provide you with the best experience we can. We also use cookies to continuously improve our website by compiling visitor statistics. Read more about cookies


Immunotherapy with CAR-T-cells

Some children require immunotherapy with CAR-T cells, for which the children's own T cells (a type of white blood cells) are first taken (harvested).The T cells are manipulated in the laboratory to enable them to recognize and destroy cancer cells. The genetically modified cells, CAR-T cells, are returned to the body via one single infusion.

Harvesting T cells

To harvest the T cells, your child is given two IV lines or a groin line. The groin line is inserted under sedation. The IV lines are connected to an apheresis machine. One line transports the blood to the machine where the T cells are harvested. The other line returns the blood without T cells.

Manipulation and return

When enough T cells have been harvested, they are sent to the laboratory where they are manipulated. The manipulation process takes some time. Once manipulated, the processed cells (CAR-T cells) are returned to your child's body via an IV.

You can find more information on this in the brochure entitled T-cell harvesting and on the Tisagenlecleucel medicine card. Please note both are currently only available in Dutch.

Should you need any further information, please feel free to ask.