Harvesting T cells
To harvest the T cells, your child is given two IV lines or a groin line. The groin line is inserted under sedation. The IV lines are connected to an apheresis machine. One line transports the blood to the machine where the T cells are harvested. The other line returns the blood without T cells.
Manipulation and return
When enough T cells have been harvested, they are sent to the laboratory where they are manipulated. The manipulation process takes some time. Once manipulated, the processed cells (CAR-T cells) are returned to your child's body via an IV.
You can find more information on this in the brochure entitled T-cell harvesting and on the Tisagenlecleucel medicine card. Please note both are currently only available in Dutch.
Should you need any further information, please feel free to ask.